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| Plasma proteins | easy to understand | Plasma proteins notes |
The Plasma proteins:
1. Serum albumin
2. Serum Hormone-Binding Globulin
3. Fibrinogen
The Serum is not only the albumin and globulin.
There is no fibrinogen in the blood serum.
as it is transformed into fibrin during blood clot formation.
The Normal use of the A/F ratio < 2: 1
THE CHARACTERISTICS OF PLASMA PROTEINS
ONCOTIC PRESSURE
The Plasma protein that is responsible for the oncotic, or osmotic pressure.
The osmotic pressure of the plasma proteins known as colloid osmotic (oncotic pressure.
Normally, this is approximately 25 mm Hg.
It plays a vital role in delivering the oncotic pressure.
SPECIFIC GRAVITY
The specific gravity of the plasma proteins is 1.026
THE BUFFER ACTION
The Plasma proteins of the show, with 1/6 of the total of the buffering action of blood.
THE ORIGIN OF THE PLASMA PROTEINS
IN THIS NO
At an early stage, which is a plasma protein that is synthesized by the mesenchyme cells. First, it is, and then the second protein to be synthesized.
ADULTS
Adults, the plasma proteins are synthesized mainly in the reticuloendothelial cells of the liver.
The Plasma proteins are synthesized, as well as the spleen, bone marrow, rotting cells and blood cells, which is a joint tissues. Gamma globulin is synthesized by B cells.
FUNCTIONS OF PLASMA PROTEINS
The Plasma proteins are very important for the human body. In the following, the functions of the plasma proteins
1. THE ROLE OF THE BLOOD'S ABILITY TO CLOT
Fibrinogen is essential for blood clotting.
2. THE ROLE OF THE BODY'S MECHANISM SECURITY
The Gamma-globulins play an important role in the body's safety mechanism, such as active antibodies (immune substances. These proteins also known as immunoglobulins.
The antibodies react with antigens of various micro-organisms as a cause of the disease, such as diphtheria, typhoid fever, streptococcal infections, mumps, influenza, measles, hepatitis b, measles, polio, etc
3. THE ROLE OF THE TRANSPORT MECHANISM
The Plasma proteins are required for the transport of various substances in the blood. Albumin, alpha-globulin and beta-globulin, which is responsible for the transport of hormones, enzymes, etc,
Alpha-and beta-globulins play an important role in the transport of metals in the blood.
4. ROLE IN THE MAINTENANCE OF OSMOTIC PRESSURE
At the capillary level of the metabolism of the majority of substances between the blood and the tissues.
However, in the plasma proteins, it is not easy to pass through the membrane to the surface of the kapilyarların function and remain in the blood stream. In the blood, a protein that indicates that the colloid osmotic (oncotic pressure.
The osmotic pressure of the plasma proteins of 25 mmHg.As the concentration of albumin is greater than that of the other plasma proteins, and the maximum pressure of the show.
Below are the hormone-binding globulin, and fibrinogen, indicating a low blood pressure.
5. THE ROLE OF THE ACID-BASE BALANCE
The Plasma proteins, especially albumin plays an important role in the regulation of the acid-base balance in the blood. This is achieved by buffering them. The Plasma proteins, with 15% of the blood buffering capacity.
6. THE ROLE OF BLOOD VISCOSITY
The Plasma protein gives blood viscosity, which is important in order to maintain the blood pressure. It allows a maximum viscosity of many other plasma proteins.
7. AN IMPORTANT ROLE IN THE LEVEL OF ERYTHROCYTE SEDIMENTATION
Hormone-binding Globulin, and fibrinogen, are accelerating the development of rulo in the formation of red blood cells. The roll of the formation is responsible for the ESR, which is an important diagnostic and prognostic tool.
8. THE ROLE OF THE STABILITY OF THE ERYTHROCYTE SUSPENSION
During the circulation of the blood, the elements are still together, suspended in the blood. This property is in the red blood cells, which is known as the suspension stability. Hormone-binding Globulin, and fibrinogen contribute to the stability of the red blood cell suspension.
9. AN IMPORTANT ROLE IN THE PRODUCTION OF VARIOUS SUBSTANCES, TREPON
Trepon of the products that are required for the nutrition of cells, tissues, and culture. These elements are produced by white blood cells, which are the plasma proteins.
10. THE ROLE OF THE PARTS OF PROTEINS
In the first place, to eat sufficiently, or insufficient intake of proteins, plasma proteins, the use of the tissues of the body, which is the final source of energy.
The Plasma proteins are broken down into the amino acids of the tissue macrophages. Amens to be taken back into the blood stream and throughout the body, which is the mobile phone of protein molecules. Therefore, a plasma protein known as the reserve of the protein.
PLAZMAFEREZ
DEFINITION
Plazmaferez, is an experimental procedure, which is performed by the animals in order to show that the value of the plasma proteins. It was formerly referred to as the Whipple experiment, as it were, to a certain extent, George Hoyt Whipple.
PROCEDURE
Plazmaferez is shown by the dogs.
The blood is completely removed from the dog's body. During this time, the blood of the parts are separated from the plasma, can be washed in a saline solution and injected into the body of the same dog, in combination with a saline solution, which is called the məhluldan her mother.Because of the sudden shortage of animal protein, is subject to a shock-like reaction.
If the animals were fed with a diet containing an adequate amount of protein, with normal levels of plasma proteins, are restored in the seven days, and it's not left.
New to the plasma proteins are synthesized in the dog's liver.If the experiment is carried out on the animals after the removal, it is also a diet sufficient in protein, plasma protein is not produced. It is a shock that affects animals and can lead to death.
Thus, the "plazmaferez" experiment, which is used to show the:
1. The importance of plasma proteins to the living
2. The synthesis of plasma and liver proteins
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